Kisspeptin reading list

Discovery and receptor function

The melanoma gene experiment and the human GPR54 puberty findings make a striking pair. For the question of duration, add the activating receptor mutation. The KISS1 loss-of-function family study concerns the peptide's own gene.

For a closer experimental view of signal transmission, the mouse GnRH-neuron work examines electrical responses in brain slices. It provides cellular context while retaining its mouse, in-vitro setting.

Hormone timing

I would start this group with the evoked LH pulse in healthy men and the response that diminished during repeated exposure. The infusion experiment in hypothalamic amenorrhea and KISS1R pharmacology review extend the timing question. The early kisspeptin-54 study in healthy men supplies a useful hormonal starting point.

Clinical experiments

The IVF trial in women at high OHSS risk sits beside work on cells collected during IVF. For desire, there is the trial in men with hypoactive sexual desire disorder and the visual and olfactory cue experiment.

I give the food-intake experiment and anxiety trial equal billing. Their unchanged outcomes sharpen the subject. The clinical-status systematic review provides a broader survey, with a literature search ending in Feb 2023.